Analytical support

The Analytical department fully supports all activities at the Reading site, including catalogue product release, evaluation of materials for in-house R&D programmes, client projects and contract analysis.

Working collaboratively within multidisciplined project teams with colleagues and clients our analytical chemists provide end-to-end support; from initial route development and optimisation to establish robust reaction schemes to target molecules, through to their final release.

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The analytical department provides a wide range of services

Raw material, intermediate, active pharmaceutical ingredient (API) and reference standard physico chemical evaluation, including, but not limited to, QC release of materials (both GMP and non-GMP), impurity profiling, specification development, method development, validation, method transfer and cleaning verification. In addition, we are able to provide stability trials and stress testing studies in accordance with ICH guidelines along with the preparation of documentation for regulatory filings.

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Contract Laboratory Analytical Service

As well as supporting our catalogue offering, R&D activities and client-based synthesis activities we also offer Contract Laboratory Analytical Service to clients. Our on-site techniques in the UK include.

Separation sciences

  • Ion Chromatography (PAD)
  • Gas Chromatography (Direct & Head Space)
  • TLC
  • Gel Electrophoresis

Spectrometric & Spectroscopic characterisation

  • NMR (1H, 13C, 19F, 31P, COSY, HMBC, DEPT, DEPT135, DEPTQ, HMQC)
  • FTIR
  • UV

Elemental & Microanalysis

  • Karl-Fischer
  • Titrations
  • Residue on ignition
  • Loss on drying

Physical chemistry

  • Melting point
  • Polarimetry

A wealth of additional techniques are available on request through our third-party analytical service provision