Heparinase II

This enzyme cleaves most links in heparin and heparin sulfate. It is relatively non-specific for 1-4 links in sulfated polysaccharide chains between hexosamines and glucuronic acid plus iduronic acids, but does not fully depolymerise either.
Optimum pH 7.0-7.6.
Stabilised with 0.2-0.4% BSA (Sigma A4378), 0.22 µm sterile filtered and dispensed into sterile tubes/vials.