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View Halogenated Nucleosides
Halogenated Nucleosides
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View Nucleotide Diphosphate Sugars
Nucleotide Diphosphate Sugars
NU001 1-(3′,5′-Di-O-benzoyl-2′-deoxy-2′-fluoro-β-D-arabinofuranosyl)-thymine
NU002 1-(3′,5′-Di-O-benzoyl-2′-deoxy-2′-fluoro-β-D-arabinofuranosyl)-5-bromo-uracil
NU003 1-(2′-deoxy-2′-fluoro-β-D-arabinofuranosyl)-thymine (D-FMAU)
NU004 5-Fluoro-1-(2′,3′-dideoxy-2′,3′-didehydro-β-D-arabinofuranosyl)-cytosine (Dexelvucitabine)
NU005 1-(2′-Deoxy-2′-fluoro-β-L-arabinofuranosyl)-uracil
NU006 1-(2′-Deoxy-2′-fluoro-3′-O-mesyl-5′-O-trityl-β-L-arabinofuranosyl)-uracil
NU007 1-(2′-Deoxy-2′-fluoro-5′-O-trityl-β-L-arabinofuranosyl)-uracil
NU008 1-(2′-deoxy-2′-fluoro-3′,5′-di-O-benzoyl-β-L-arabinofuranosyl)-uracil
NU009 5-Fluoro-1-(2′-deoxy-2′-fluoro-3′,5′-di-O-benzoyl-β-L-arabinofuranosyl)-uracil
NU011 1-(2′-Deoxy-2′-fluoro-α-L-arabinofuranosyl)-thymine (alpha-Clevudine)
NU012 1-(2′-Deoxy-2′-chloro-β-L-arabinofuranosyl)-thymine
NU013 5-Fluoro-1-(β-L-ribofuranosyl)-uracil
NU014 1-(2′,3′-Dideoxy-2′,3′-didehydro-2′-fluoro-5′-O-trityl-β-L-ribofuranosyl)-uracil
NU015 5-Fluoro-1-(2′,3′-dideoxy-2′,3′-didehydro-5′-O-acetyl-β-L-ribofuranosyl)-uracil
NU016 5-Fluoro-1-(2′-deoxy-2′-fluoro-5′-O-trityl-β-L-lyxofuranosyl)-uracil
NU017 5-Fluoro-1-(2′-L-menthyloxycarbonyl-1′-3′-oxathiolan-5′-yl)-cytosine
NU101 UDP-a-D-galactose (ammonium salt)
NU102 UDP-2-deoxy-a-D-galactose (ammonium salt)
NU103 UDP-a-N-acetyl-D-galactosamine (ammonium salt)
NU104 UDP-a-D-glucose (ammonium salt)
NU105 UDP-b-L-glucose (ammonium salt)
NU106 TDP-a-D-glucose (ammonium salt)
NU107 TDP-a-D-fucose (ammonium salt)
NU108 TDP-b-L-rhamnose (ammonium salt)
NU109 GDP-b-L-glucose (ammonium salt)
More information
What are Nucleosides & Nucleotides?
Naturally occurring nucleosides are glycosylamines comprising of a 5-carbon ribose or 2-deoxyribose sugar bound to a nucleobase via a β-glycsidic bond. Nucleosides are the precursors to the nucleotide building blocks of DNA and RNA and can be subdivided into two classes relating to their nucleobase subunit, pyrimidines (cytidine, thymidine and uridine) and purines (guanosine and adenosine).
Nucleotides are comprised of a nucleobase, ribose or deoxyribose sugar and one or more phosphate groups. In addition to their role as fundamental building blocks of DNA and RNA, nucleotides are also key in cell metabolism (as the nucleoside triphosphates ATP, GTP, CTP and UTP) and cell signalling (cGMP and cAMP).
Synthetic Nucleosides & Nucleotides
Synthetic nucleoside and nucleotide analogues have been used successfully in the treatment of a wide range of clinical indications. Examples include azidothymidine (AZT) and abacavir in the treatment of HIV and ribavirin in the treatment of a range of viral diseases. Other indications where nucleoside analogues are used in the clinic include cancer, varicella zoster and herpes simplex.