Dextra are pleased to offer a range of N-glycans isotopically labelled with 13C, for use as quantitative standards. Utilisation of this panel of isotopically labelled glycan standards greatly simplifies the direct analysis of intact glycans by MALDI-TOF MS, thus providing a distinct advantage over alternative approaches in terms of ease of use, speed, data content and accuracy. These are available as single standards or in kit form.
Changes in protein glycosylation are a hallmark of many cancers, infectious and autoimmune diseases and the growing number of congenital disorders of glycosylation (CDG) suggests an increasingly important role for glycans as biomarkers.
These standards can be utilised across a wide range of applications including:
- Biopharmaceutical Development
- Clinical Chemistry Biomarkers